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Thursday, 6 October 2016

Researchers in Bradford find new way of stopping some cancers resisting chemotherapy

Researchers in Bradford find new way of stopping some cancers resisting chemotherapy
Researchers in Bradford find new way of stopping some cancers resisting chemotherapy

Researchers in Bradford find new way of stopping some cancers resisting chemotherapy

UNIVERSITY researchers in Bradford say they have discovered a new way of stopping lung and breast cancer cells resisting chemotherapy in a breakthrough that could save lives.
Experts at Bradford’s Institute of Cancer Therapeutics, led by Professor Mohamed El-Tanani, now need to find funding from cancer research funders, pharmaceutical companies and investors to start clinical trials on patients.
Researchers, in collaboration with Queen’s University Belfast, have screened millions of potential drugs to come up with two strong contenders they believe would block a cancer-inducing protein called Ran-GTP found in patients’ diseased cells.


Their findings were published in medical journal Oncotarget this week and have excited Cancer Research UK.
The charity’s science information officer Catherine Pickworth said: “When cancer becomes resistant to chemotherapy it’s a lot harder to treat. Excitingly, this study has identified a potential target to stop or even reverse cancer resistance to a chemotherapy drug called Gefitinib. Now more research and clinical trials are needed to find and test a drug that will help patients whose cancers have become resistant to chemotherapy.”
One of the drugs researchers want to trial is already known to be safe for humans and the other has been tested on mice, which means clinical tests on patients could start even sooner.



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